Best Gestalt Therapies In Frankfurt Near Me

4worldlovers: Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded. Degradation, known as ER-phagy, is promoted by the protein ubiquitin, which controls many processes in the cell. If the proteins involved in ER-phagy are defective, neurodegenerative diseases result. This has been discovered by an international research team led by Goethe University Frankfurt (as part of the EMTHERA research cluster) and Jena University Hospital and published in two papers in the renowned journal Nature.

All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals

Identifying connections between distinct neurons and their contribution to driving behaviour is a central issue in neuroscience. To explore such relations, methods to record and concurrently regulate neural activity are needed. Excitable cells can be stimulated or inhibited by optogenetics. Since optogenetic actuation regimes are often static, neurons and circuits can quickly adapt, allowing perturbation, but not true control. A team of scientists now managed to develop an optogenetic voltage-clamp (OVC).

Puzzle around a protein - Researchers from Frankfurt and Ulm provide important insights into the rare PURA Syndrome

Computational biologist Kathi Zarnack investigates what happens in the cells of patients with PURA Syndrome, a genetically determined neurodevelopmental disorder. In a study conducted jointly with Dierk Niessing at the University of Ulm, she has now come a significant step closer to solving the mystery. The study showed that the regulation and quality control of messenger RNAs in the cells were affected. Their findings about molecular and cellular networks could provide approaches to future therapy studies for the hitherto incurable disease.